Geometry and epithelial repair

We will present work on the mechanisms used for establishing or restoring epithelial integrity which are motivated by experimental work on development and wound healing in Zebrafish and drosophila and on gap closure in monolayers of MDCK cells or keratinocytes. These works concern mathematical modeling of the dynamics of epithelial tissues pulled by lamellipodal crawling or the contraction of actomyosin cables at the gap boundary. We are particularly interested in the influence of the wound/gap geometry on the closure mechanism.

This seminar is organized within the Research project MFAG 17412 «Mathematical insights of glioblastoma growth: a mechano-biology approach for patientspecific clinical tools» funded by the Italian Association for Cancer Research (AIRC), Project coordinator Prof. Pasquale Ciarletta