Head of Dept: Prof. Giulio Magli
Vice-Head of Dept: Prof. Gabriele Grillo
Department Manager: Dr.ssa Franca Di Censo
﻿
• 2019 RISM Congress: Modelling the Cardiac Function - iHEART
Three days of lectures to focus on the latest achievements in modelling the heart function. For updated program and details for registration, please see http://iheart.polimi.it/mcf2019

### Upcoming Events

•  jun 24 mon 2019 Seminar Lorenzo Giacomelli, The mathematics of spreading droplets,  06-24-2019, 16:30 precise

• Seminar
• Lorenzo Giacomelli
• Università La Sapienza, Roma
• The mathematics of spreading droplets
• Monday, 24 June 2019 at 16:30 right
• Sala Consiglio, 7 piano, Edificio La Nave, Via Ponzio 31-33
• Abstract
Wetting phenomena at small scales are an area where chemistry,
physics, mathematics, and engineering intersect. In recent years,
driven also by molecular dynamics, new concepts have been introduced
to describe the statics and dynamics of wetting, allowing new
insights into the old problems of surface forces. Among these
problems, two prominent ones are an appropriate mathematical modeling
of the moving contact line where liquid, solid, and surrounding vapor
meet, and how such models influence the macroscopic properties of the
flow. After a general framing -- the classical setting of droplets'
statics and dynamics, diffuse and sharp interface models, classical
and new descriptions of the contact line -- I shall review the PDE
theory for one of such models -- the so-called thin-film equation --, mainly focusing on the two aforementioned problems and on some of the most interesting current challenges.
• Politecnico di Milano, Dipartimento di Matematica via Bonardi 9, 20133 Milano - Telefono: +39 02 2399 4505 - Fax: +39 02 2399 4568

•  jul 02 tue 2019 Seminar Colette De Coster, A prescribed anisotropic mean curvature equation modeling the corneal shape: a paradigm of nonlinear analysis,  07-02-2019, 15:15

• Seminar
• Colette De Coster
• Univ. Valenciennes
• A prescribed anisotropic mean curvature equation modeling the corneal shape: a paradigm of nonlinear analysis
• Tuesday, 2 July 2019 at 15:15
• Aula seminari 3° piano
• Abstract
In this talk, we survey some recent results concerning the Dirichlet problem for the prescribed anisotropic mean curvature equation
\begin{equation*}
{\rm -div}\left({\nabla u}/{\sqrt{1 + |\nabla u|^2}}\right) = -au + {b}/{\sqrt{1 + |\nabla u|^2}},
\end{equation*}
in a bounded Lipschitz domain $\Omega \subset \RR^N$, with $a,b>0$ parameters.
This equation appears in the description of the geometry of the human cornea, as well as in the modeling theory of capillarity phenomena for compressible fluids.

In this talk, we show how various techniques of nonlinear functional analysis can successfully be applied to derive a complete picture of the solvability patterns of the problem.
• Politecnico di Milano, Dipartimento di Matematica via Bonardi 9, 20133 Milano - Telefono: +39 02 2399 4505 - Fax: +39 02 2399 4568

•  jul 11 thu 2019 MOX Seminar Series Kent - Andre Mardal, Preconditioning of multiphysics problems with applications to the biomechanics of the brain,  07-11-2019, 14:00

• MOX Seminar Series
• Kent - Andre Mardal
• University of Oslo and Simula Research Laboratory
• Preconditioning of multiphysics problems with applications to the biomechanics of the brain
• Thursday, 11 July 2019 at 14:00
• Aula consiglio VII piano, Edificio 14, Dipartimento di Matematica POLITECNICO DI MILANO
• Abstract
In this talk we will discuss preconditioning algorithms for monolithic schemes of coupled problems involving the coupling of porous and viscous flow as well as fluid-structure interaction and dimension reduction problems.
We explore how fractional Laplacian solvers may be utilized to obtain parameter robust schemes. The schemes are discussed in the context of biomechanical modelling of the waste clearance processes in the brain that is believed to fail in various forms of dementia such as Alzheimer's and Parkinson's diseases.

Contact: paolo.zunino@polimi.it

• Kent-Andre Mardal is a Professor at the University of Oslo and an adjuct researcher at Simula Research Laboratory. His research focus is on computational methods for life-science applications, where focus areas are robust multi-physics algorithms, high-performance preconditioning techniques, generic scientific software components, the microcirculation and metabolism of the brain, the cause of dementia such as Alzheimer’s disease and normal pressure hydrocephalus, and multi-dimensional coupling problems. Mardal has made core contributions to the FEniCS software library, the operator preconditioning technique, demonstrated transitional flow at low Reynolds number in blood flow and made crucial observations concerning the g-lymphatic system potentially involved in Alzheimer´s disease development.
• Politecnico di Milano, Dipartimento di Matematica via Bonardi 9, 20133 Milano - Telefono: +39 02 2399 4505 - Fax: +39 02 2399 4568

•  jul 18 thu 2019 Seminar Caterina La Porta, Complexity in biomedicine,  07-18-2019, 10:00

• Seminar
• Caterina La Porta
• Università degli Studi di Milano
• Complexity in biomedicine
• Thursday, 18 July 2019 at 10:00
• Dipartimento di Matematica - 7° piano, Politecnico di Milano
• Abstract
In this talk, I will discuss our recent advances in understanding phenotypic plasticity of cancer cells using a combination of experiments, analysis of big data and computational models of complex regulatory networks. Next, I will discuss our results on protein aggregation in neurodegenerative pathologies, such as Alzheimer's and Huntington's disease.

In particular, I will report on the importance of protein clearance from the endoplasmic reticulum to drive protein aggregation and on our recent results on huntingtin heterogenous aggregation in which mutated forms of the protein are able to form oligomers with non-mutated forms.
• Politecnico di Milano, Dipartimento di Matematica via Bonardi 9, 20133 Milano - Telefono: +39 02 2399 4505 - Fax: +39 02 2399 4568

•  jul 22 mon 2019 jul 24 wed 2019 WorkShop Rism 2019 - modelling the cardiac function - iheart 07/22/2019 - 07/24/2019

• WORKSHOP
• MCF2019
Rism 2019 - modelling the cardiac function - iheart
• organizers
A. Quarteroni, L. Dedè, A. Manzoni, S. Serra-Capizzano, C. Vergara, P. Zunino
• This congress, organised in the context of the prestigious Riemann International School of Mathematics, aims at focusing on the state of the art in the mathematical modelling and numerical simulation of the cardiac function and its clinical applications. This event will host 8 plenary lectures from distinguished scientists as well as contributed talks some presented by PhD students and some by senior researchers, and a poster session. PhD students selected for contributed presentation will be offered free accommodation. The Congress is organized by RISM and MOX - Politecnico di Milano, and is partially supported by the EU ERC-ADG - Advanced Grant iHEART Project ID: 740132 - iheart.polimi.it
• Monday, 22 July 2019 - Wednesday, 24 July 2019
Villa Toeplitz - Varese
Politecnico di Milano, Dipartimento di Matematica via Bonardi 9, 20133 Milano - Telefono: +39 02 2399 4505 - Fax: +39 02 2399 4568