Codice MOX 65 Titolo A numerical study for comparing two response-adaptive designs for continuous treatment effects Data 2005-07-26 Autore/i Paganoni, Anna Maria; Secchi, Piercesare Link Download full text Pubblicato A.M.Paganoni, P.Secchi (2007), A numerical study for comparing two response-adaptive designs for continuous treatment effects, Statistical Methods and Applications, 16, 321-346 Abstract We study two sequential, response-adaptive randomized designs for clinical trials one has been proposed in Bandy-opadhyay and Biswas (2001) and Biswas and Basu (2001), the other stems from randomly reinforced urn introduced and studied in Muliere et al.(2005). Both designs can be used in clinical trials where the response from each patient is a continuous variable. Comparison is conducted through numerical studies and along a new guideline for the evaluation of a response-adaptive design