Codice 41/2013 Titolo Analysis of Proteomics data: Block K-mean Alignment Data 2013-10-04 Autore/i Bernardi, M.; Sangalli, L.M.; Secchi, P.; Vantini, S. Link Download full text Pubblicato Mara Bernardi, Laura M. Sangalli, Piercesare Secchi, Simone Vantini (2014), Analysis of Proteomics data: Block K-mean Alignment, Electronic Journal of Statistics, Special Section on "Statistics of Time Warpings and Phase Variations", Vol. 8, No. 2, 1714-1723. Abstract We analyze the proteomics data introducing a block k-mean alignment procedure. This technique is able to jointly align and cluster the data, accounting appropriately for the block structure of these data, that includes measurement repetitions for each patient. An analysis of area-under-peaks, following the alignment, separates patients who respond and those who do not respond to treatment.